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Katti, Sachin; Igumenova, Tatyana I. (, Advances in Biological Regulation)null (Ed.)
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You, Youngki; Katti, Sachin; Yu, Binhan; Igumenova, Tatyana I.; Das, Joydip (, Biochemistry)null (Ed.)
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Katti, Sachin; Nyenhuis, Sarah B.; Her, Bin; Cafiso, David S.; Igumenova, Tatyana I. (, Biophysical Journal)
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Katti, Sachin; Igumenova, Tatyana_I (, Metallomics)Abstract Pb2+ is a xenobiotic metal ion that competes for Ca2+-binding sites in proteins. Using the peripheral Ca2+-sensing domains of Syt1, we show that the chelating pH buffer Bis–Tris enables identification and functional characterization of high-affinity Pb2+ sites that are likely to be targeted by bioavailable Pb2+.more » « less
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